IntelliPlex™ NRAS Mutation Kit

The IntelliPlex™NRAS Mutation Kit is a qualitative molecular assay for the detection of 33 somatic mutations on exons 2, 3 and 4 of the NRAS gene in formalin-fixed paraffin-embedded tissue (FFPET). A total of 33 mutations can be identified in a single well by using PlexBio's core πCode™ technology.

FEATURES

Detect 33 somatic NRAS mutations in one well test
Highly sensitive (0.14%-6.48%) to detect low levels of mutant DNA
Only 10ng DNA sample required
Time to results in <6 hours for 96 samples per run (sample preparation included)

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Multi-targets Detection

Detectable 33 NRAS mutations in one well

Low Sample Input

Only 10ng DNA sample extracted from FFPE tissues required

High Sensitivity

Detects low levels of mutant DNA with a high sensitivity

Quick Turnaround Time

Sample to results in <6 hours with automated reporting

Overview

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Overview

The IntelliPlex™ NRAS Mutation Kit is an in-vitro molecular test based on πCode™ technology and PlexBio's instrument platform to identify 33 nucleotide changes on exons 2, 3 and 4 of the NRAS gene. πCode™ technology enables the multi-mutations detection in single-well with DNA samples derived from formalin-fixed paraffin-embedded (FFPE) human tissues. The kit provides all necessary optimized reagents for the sensitive detection of low levels of mutant DNA in a background of wild-type genomic DNA by simultaneous PCR amplification of target mutations. The testing results could deliver crucial molecular status to clinical evaluation.

Principle of πCode Multiplexing

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