Catalog Number:82004

IntelliPlex™ BRAF V600 Mutation Kit

The IntelliPlexTM BRAF V600 Mutation Kit is a qualitative molecular assay for the detection of somatic mutations on exon 15 of the BRAF gene in formalin-fixed paraffin-embedded tissue (FFPET).  A total of 7 mutations can be identified in a single well by using PlexBio's core πCode technology.

FEATURES
  • Detect 7 BRAF V600 mutations in one well test
  • Highly sensitive (0.29%-1.57%) to detect low levels of mutant DNA
  • Only 10ng DNA sample required
  • Time to results in <6 hours for 96 samples per run (sample preparation included)
multiplexing

Multi-targets Detection

Detectable 7 BRAF codon 600 mutations in one well
sample

Low Sample Input

Only 10ng DNA sample extracted from FFPE tissues required
high sensitivity

High Sensitivity

Detects low levels of mutant DNA with a high sensitivity
quick turnaround time

Quick Turnaround Time

Sample to results in <6 hours with automated reporting 
Overview
The IntelliPlexTM BRAF V600 Mutation Kit is an in-vitro molecular test based on πCodeTM technology and PlexBio's instrument platform to identify 7 nucleotide changes in exon 15 of the BRAF gene. πCode technology enables the multi-mutations detection in single-well with DNA samples derived from formalin-fixed paraffin-embedded (FFPE) human tissues. The kit provides all necessary optimized reagents for the sensitive detection of low levels of mutant DNA in a background of wild-type genomic DNA by simultaneous PCR amplification of target mutations. The testing results could deliver crucial molecular status to clinical evaluation.

Principle of πCode Multiplexing

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